Background: In recent decades, several studies have shown that hyperhomocysteinemia is an independent risk factor for atherosclerosis. The objective of this work is, first, to assess the atherogenic potential of homocysteine in rats and and appraise its effect on endothelial cells: the main components of the blood vessel.

Lichens are used since antiquity for multiple therapeutic purposes, treating infections, fever, convulsions, and wounds. This study was designed to evaluate the antioxidant and anti Hale. The total phenolics and flavonoids content were determined in ethanol extract; the antioxidant activity was assessed by different chemical assays DPPH (1,1acid)), β-carotene-linoleic acid, reducing power, and further tested in vitro, for its anti-inflammatory effect through the bovine serum albumin denaturation assay; inflammatory response was investigated on the LPS intercellular ROS (Reactive Oxygen Species) and TNF in the extract was determined by High extract contained high levels of total phenolics than flavonoids, and had an antioxidant effect; it prevented the protein denaturation in a dose-dependent manner, also reduced the intracellular ROS and TNF Furthermore, it did not affect the viability of different findings, P.hypotropa can constitute a po inflammatory effects.