Objectives: To summarize the combination of different Orthodontic treatment protocols and different Surgery techniques required in the management of patients born with cleft lip and/or palate. Materials and methods: We searched the relevant articles from PubMed, on the web of science, EMBASE, Google scholar and manually search by using the following search terms: "Orthodontic management and cleft lip or palate", "Post orthodontic management and cleft lip or palate" "surgery techniques and cleft lip or palate" all relevant articles in English language published from 2007 to 2017 were reviewed. Abstracts and title were evaluated and full-text analysis was performed, we excluded abstracts without full articles, articles published not in English language, Case reports, and all types of review. Results: A total of 8 articles were included in the qualitative synthesis, they were of retrospective and cohort study design. Four articles1−4 assessed the surgical timing of cleft repair and favored early (mixed dentition) over late (permanent dentition) Secondary Alveolar bone grafting (SABG). The studies on postoperative orthodontic treatment5−8 and concluded that maxillary expansion and surgical advancement are generally needed for most cleft palate patients. Conclusion: Orthodontic treatment plays an integral role in the rehabilitation phase toward the preparations of alveolar bone grafting and orthognathic surgery.