Proses membangun pengetahuan merupakan dasar dari suksesnya pembelajaran. Pembelajaran di Abad 21 menitikberatkan pada kompetensi yang digunakan untuk mengatasi permasalahan sehari-hari. Keterampilan metakognitif merupakan keterampilan siswa mampu merefleksikan apa yang mereka pelajari. Siswa yang memiliki keterampilan metakognitif diharapkan mampu menguasai konsep-konsep genetika. Tujuan dari penelitian ini adalah untuk mendeskripsikan pengetahuan genetika dan keterampilan metakognitif siswa dalam praktikum isolasi DNA berdasarkan model pembelajaran berbasis proyek. Subjek  dari  penelitian  ini  adalah  siswa  kelas  XII  di  salah  satu  SMA  di  Tuban Jawa Timur.  Untuk keterampilan  metakognitif,  digunakan instrumen  Metacognitive  Awareness  Inventory  yang  dimodifikasi  dari  Schraw  dan Dennison  (1994). Hasil penelitian menunjukkan bahwa sebagian  besar  siswa  yang  diuji memiliki  tingkat  keterampilan metakognitif dalam kategori berkembang sangat baik sebesar 50%, berkembang baik 36% dan mulai berkembang 13%. Ditinjau dari indikator metakognitif menunjukkan bahwa secara keseluruhan siswa memiliki keterampilan metakognitif yang berkembang sangat baik dan baik. Namun siswa masih memiliki kelemahan dalam indikator evaluasi yang masih terdapat keterangan keterampilan metakognitif siswa belum berkembang sebesar 1%. Hal ini menunjukkan bahwa semakin tinggi keterampilan metakognitif siswa berdampak terhadap hasil tes pengetahuan genetika. Hasil tes pengetahuan genetika menunjukkan pengetahuan siswa dalam kategori tinggi sampai sedang. Keterampilan metakognitif berperan dalam meningkatkan pengetahuan genetika yang didukung dengan praktikum isolasi genetika yang berdasarkan model pembelajaran berbasis proyek.   Abstrack: The process of building knowledge is the basis of successful learning. Learning in the 21st Century focuses on competencies that are used to solve everyday problems. Metacognitive skills are skills students are able to reflect on what they learn. Students who have metacognitive skills are expected to be able to master genetic concepts. The purpose of this study was to describe the genetic knowledge and metacognitive skills of students in DNA isolation practicum based on a project-based learning model. The subjects of this study were students of class XII in one of the senior high schools in Tuban, East Java. For metacognitive skills, a modified Metacognitive Awareness Inventory instrument was used from Schraw and Dennison (1994). The results showed that most of the students tested had a metacognitive skill level in the category of very well developed by 50%, well developed 36% and starting to develop 13%. In terms of metacognitive indicators, it shows that overall students have metacognitive skills that are very well developed and well developed. However, students still have weaknesses in the evaluation indicators and there is still a description of students' metacognitive skills that have not developed by 1%. This shows that the higher students' metacognitive skills have an impact on the results of the genetic knowledge test. The results of the genetic knowledge test showed students' knowledge in the high to medium category. Metacognitive skills play a role in increasing genetic knowledge, supported by genetic isolation practicum based on a project-based learning model.

Science Process Skills (SPS) need to be developed to improve teacher quality in teaching. The existence of the Covid-19 pandemic caused Biology teachers to be unable to carry out practicums so the SPS were helpless. This study aims to analyze the science process skills of biology teacher candidates in vertebrate zoology courses. The research method used is descriptive quantitative through survey techniques. This research was conducted at the PGRI Ronggolawe University and involved 21 participants. This study uses an instrument in the form of an observation sheet to measure scientific process skills. The SPS indicators that are measured are the skills of observing, measuring, compiling tables, and obtaining and processing data. The data obtained is then interpreted into very high, high, low, and very low categories. The percentage of students in each category is then calculated as a map of their science process skills through analysis of quantitative descriptive data. The results showed that 65.5% of prospective biology teachers had SPS scores that were in the very high, high, low, and very low categories. 7.5% has an SPS value which is included in the very low category. In general, biology teacher candidates tend to have very high levels of competency in performing science process skills.

Modules are teaching materials that are indispensable in learning to assist teachers in delivering learning materials in order to improve student competence, one of which is critical thinking skills. This study aims to produce products in the form of cell division control modules to develop critical thinking skills. The method used in this research is ADDIE (Analyze, design, develop, implement, and evaluate). Modules are validated by media experts, materials experts, field practitioners, and readability and practicality trials. The results of validation by material expert validators, media expert validators and field practitioners, were obtained respectively 91.02%, 91.41%, and 90.21% with very valid criteria and can be used without the need for revision. The results of the practicality test are 91.25% with very practical criteria and can be used without the need for revision.