Complete deficiency of lactate dehydrogenase (LDH) subunit H was identified in a 41-year-old woman with paralysis of her left lower limb. The propositus had extremely low LDH activity and five of her family members had levels of LDH activity that ranged from lower than normal to normal level. A transversion mutation at codon 171 (CGC→CCC), resulting in an Arg→Pro substitution was identified in her DNA sequence. A new NruI restriction site was introduced into the polymerase chain reaction (PCR) product by PCR-primer introduced restriction analysis (PCR-PIRA) using a specific mismatched primer. Digestion with NruI revealed that the propositus and her mother were, respectively, homozygous and heterozygous for this mutation.
To realize the economical and high performance drive for urban transit, a linear motor is driven as a high performance expensive motor or a economical secondary sheet type linear induction motor (LIM) with relative poor performance which is in practical application, by changing the reaction rail, not changing the primary on vehicle. First, it is discussed the secondary wound type LIM without end effect. It is revealed that the wound type LIM has much larger secondary leakage reactance than sheet type LIM, and the performance is not good in this use. Second, the linear synchronous motor (LSM) is discussed as a high performance motor. It is cleared that LSM realizes both the short primary and high efficiency with unity power factor even in the practical section length for the field excitation. So, authors propose the combination use of LSM in power running or braking region and sheet type LIM in other region.
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