Data presented in this study include sex- and delivery-mode-specific BP percentile curves using an oscillometric method and serve as a valuable reference for physicians in dealing with the management of singleton, liveborn late preterm and term newborns in the delivery room intensive care.
Objective: Nowadays nearly, Acinetobacter baumanniihas become an incurable nosocomial infections’ pathogendue to its ability developing multiple resistance againstantibiotics strains In our study, it was aimed to determinerates of resistance of A. baumannii strains isolated fromvarious samples in the Dicle University Hospital.Methods: A. baumannii culture results of 270 patientsthat were followed in the Dicle University Medical FacultyHospital between June 2010 and June 2011 wereevaluated. Resistance rates of A. baumannii strains werecultured by conventional methods and BD Phoenix (BDDiagnostic Systems, Sparks, MD) automated system.Results: Our study included 82 (30.4%) female and 188(69.6%) male. Resistance rates of A. baumannii strainswere as follows: amikacin (76%), ampicillin / sulbactam(94%), aztreonam (96%), cefepime (95%), cefotaxime(98%), ceftazidime (95%), ciprofloxacin (93%), colistin(6%), gentamicin (94%), imipenem (87%), levofloxacin(87%), meropenem (87%), piperacillin / tazobactam(92%), tetracycline (84%), trimethoprim / sulfamethoxazole(82%).Conclusions: A. baumannii strains isolated from ourcultures have very high rate of resistance against antimicrobialagents except colistin. It should not be forgottenthat antibiotic susceptibility may change from year to yearin the regions, hospitals and even clinics, and resistancerates should be continuously monitored. When selectingempiric treatment, resistance rates of A. baumannii of thatlocation should be considered until having culture results.In the infections caused by A. baumannii cultures and antibiogramsshould be repeated during treatment becausethat A. baumannii strains may change resistance ratio. JClin Exp Invest 2013; 4 (3): 318-321Key words: A. baumannii, antibiotic, resistance
In these case series, we report on six children (3 girls, 3 boys) aged 5-13 years with Henoch-Schönlein purpura (HSP) who developed severe gastrointestinal (GI) bleeding resistant to both 2 mg/kg or pulse (10-30 mg/kg) i.v. methylprednisolone. All patients responded to single-dose (500 mg/m(2) ) i.v. cyclophosphamide (CPA) and none of them developed new GI bleeding after CPA treatment. No patients required surgical intervention. Single high-dose CPA may be beneficial in HSP with severe GI involvement, in which bleeding is non-responsive to high-dose steroids.
ÖZETAmaç: Bu çalışmanın amacı, indirekt hiperbilirübinemi nedeni ile Yenidoğan Ünitesi'ne yatırılan olguların özellik-lerini ortaya koymayı ve indirekt hiperbilirübinemi açısın-dan risk faktörlerini belirlemektir. Gereç ve yöntem:Bu çalışmada Yenidoğan Ünitesinde, yatırılarak tedavi edilen gebelik yaşı 35 hafta ve üzerinde olan 222 indirekt hiperbilirubinemili yenidoğan incelendi. Hastaların fizik muayeneleri ve laboratuvar çalışmaları yapıldı. Fototerapi ve kan değişimi kararı Amerikan Pediatri Akademisi'nin önerilerinde bildirilen total serum bilirü-bin (TSB) değerlerine göre verildi. Bulgular: Çalışma grubundaki olguların 131'i (%59) erkek, 91'i (%41) kız idi. Kız ve erkek bebekler arasında TSB değerleri açısından aralarında anlamlı fark bulunmadı (p>0.05). Olgularımızın %71.2'sini term bebekler, %19.8'ini 35-37 gebelik haftasındaki geç preterm bebekler oluşturuyordu. Spontan vajinal yolla doğan olguların yatış TSB değerleri, sezaryen ile doğan olgulara göre sınırda yüksek bulundu. (p=0.051). Olguların %30.1'inde ABO kan grubu uygunsuzluğu, %6.7'sinde Rh grup uygunsuzluğu saptandı. Hastaların 49'unda (%22.7) yetersiz beslenme ve yetersiz kalori alımı, 19 (%8.5)'unda üriner sistem enfeksiyonu, 9 (%4.05)'unda hipernatremik dehidratasyon, saptandı. On (%4.5) hastaya kan deği-şimi uygulandı ve iki olguda kernikterus gelişti. Sarılıklı bebeklerin doğum tartıları ile yatış TSB düzeyi arasında negatif korelasyon (p<0.05), yüzdelik tartı kaybı oranı ile yatış TSB düzeyi arasında pozitif korelasyon saptandı (p<0.05).Sonuç: Çalışma sonuçlarımıza göre yenidoğanlarda sarılığa yol açan en sık etiyolojik nedenler, ABO kan grubu uygunsuzluğu, yetersiz beslenme ve geç pretermlik olarak saptandı.Anahtar kelimeler: İndirekt hiperbilirübinemi, etyolojik faktörler, kernikterus, geç preterm ABSTRACT Objectives: The aim of this study was to investigate characteristics of neonates hospitalized to Neonatal Unit due to indirect hyperbilirubinemia and to determine risk factors for indirect hyperbilirubinemia. Materials and methods:Totally 222 newborns, aged ≥35 weeks of gestational age and hospitalized in neonatal unit with indirect hyperbilirubinemia, were investigated. Physical examination and laboratory studies of children were performed. Decision of phototherapy and exchange transfusion was done according to total serum bilirubin (TSB) level that notified in the Guidelines of American Academy of Pediatrics.Results: Study group consisted of 131 (60%) male and 91 (30%) female newborns. No significant difference was found in TSB values between male and female neonates. There was 71.2% term and 19.8% late preterm newborn babies. Babies born with spontaneous vaginal delivery had borderline higher TSB values compared with cesarean section deliveries (p=0.051). ABO blood group incompatibility was found in 30.1% and Rh incompatibility in 6.7%. Insufficient nutrition and inadequate caloric intake were found in 49 (22.7%) of neonates, urinary tract infection in 19 (8.5%), hypernatremic dehydration in 9 (4.5%) and hypothyroidism in 4 (2.0%)....
Objective: Burn wound infections are the most severe cause of mortality in patients in the burn units. The aim of this study is to determine the bacteriological profile and their antibiotic resistance patterns in burn unit of Dicle University Hospital. Methods: Medical records of 151 burn patients admitted to the burn unit of Dicle University Hospital between June, 2008 and June 2010 were reviewed retrospectively. Results: Our study included 70.2% (n=106) male and 29.8% (n=45) female patients. The mean age of cases was 10.9±14.7 years. The rate of isolated microorganisms were 62.3% (n=94) Acinetobacter baumannii, 25.8% (n=39) Pseudomonas aeruginosa, 7.3% (n=11) Escherichia coli and 4.6% (n=7) Staphylococcus aureus. The most effective antibiotic against A. baumannii was colistin (95%) followed by levofloxacin (84%) and trimethoprimsulfamethoxazole (87%). The most effective antibiotics against P. aeruginosa were amikacin (82%), ciprofloxacin (71%) and levofloxacin (71%). The most effective antibiotics against E. coli were amikacin (91%), meropenem (73%) and imipenem (82%). Conclusion: The prevalence of burn wound infection caused by A. baumannii and multiple drug resistant A. baumannii are increasing worldwide by time. The prevalence of multiple drug resistant P. aeruginosa and E. coli are rising also. So, new strategies of infection prevention should improve as soon as possible.
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