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Medical tourism industry is an international phenomenon, which most of medical tourists for some reasons such as high costs of treatment, long waiting queues, lack of insurance and lack of access to health care in the origin country, travel long distances to benefit from health care services of destination country. Given the competitive nature of this industry, most countries are designing practical and legal services and planning for their development. For this purpose, this study has been conducted to develop a strategic planning framework for development of medical tourism industry in Yazd province of Iran; because in recent years Yazd has recognized as the health pole by patients in developing countries. In sum, emphasizing on servicing, enhancing and developing specialized treatment centers, has attracted patients from center, south and east of the country as well as Middle East and Central Asia countries. The dominant approach in this study is developmental -practical and also the research method is descriptive, analytical and survey. In order to analyzing the data, the SWOT model and best-worst techniques have been used. In the following, after identifying strategic position of Yazd province in terms of medical tourism industry, the related strategies were formulated and practical results were presented.