A straightforward strategy for direct incorporation of sulfonyl units into xanthene moiety for accessing xanthen-9-sulfone derivatives in good to excellent yields has been established via metal-free radical-radical cross-coupling reaction of...

We report an atom-economic Rh­(III)-catalyzed [3 + 2]-spiroannulation reaction between cyclic ketimines and α,β-unsaturated carbonyl compounds, allowing the synthesis of novel spirocycles with concomitant generation of three stereogenic centers in one pot. The reaction does not require any silver additives or external oxidants and is believed to proceed in a redox-neutral manner. A broad substrate scope with good functional group tolerance permitted the synthesis of a vast spectrum of spirocyclic 1,4-benzoxazine derivatives containing polysubstituted α-aroyl-indanamines in good to excellent yields with high diastereoselectivity.

We report an unprecedented atom-economic one-pot Cp*Rh(III)-catalyzed regioselective [3 + 2]-spiroannulation reaction between dibenz(ox)azepines and ynones, allowing the synthesis of biologically relevant novel spirocyclic dibenz(ox)azepines under operationally simple and mild...

A straightforward strategy for direct access of C-9 functionalized N-alkyl-acridanes in good to excellent yields has been established via metal and external oxidant-free sustainable electrochemical C(sp3)-C(sp3) cross-dehydrogenative coupling reaction between...