BackgroundSickle cell disease (SCD) is a common hematological disorder with a high prevalence in Saudi Arabia. Despite that, limited studies are available in our region regarding cardiovascular complications. ObjectivesThe objective of the current study was to estimate the prevalence of cardiovascular complications among children with SCD. DesignThis was a cross-sectional study. SettingThe study took place at a single tertiary-care center in Jeddah, Saudi Arabia.