SummaryLithuania among the middle-income countries is experiencing the brain drain situation when high-educated professionals, including health care specialists, migrate to high-income countries in search for better economic, social and cultural life. The objective of the study was to identify the potential reasons for migration from the perspective of pharmacy students that might come into consideration after they graduate university. A convenience sample (n = 196) of pharmacy students participated in the cross-sectional survey where they gave opinion on why people emigrate from Lithuania, also expressed personal attitude towards emigration, as well as intention to emigrate after the studies on self-report scales. The nonlinear Robust Path Analysis approach was employed for data analysis. The results revealed that high unemployment conceived as a reason to emigrate from Lithuania, as well as personal attitude towards emigration was significantly linked with intent to emigrate after studies. Family or friends living abroad, adverse cultural environment, and lack of entertainment options conceived as a reason to emigrate significantly affected students personal attitude towards emigration from Lithuania. High unemployment as a reason for emigration remained the main factor directly associated with the intention to emigrate. However, investment in social, cultural and human capital should be seen as the next step to reduce the attractiveness of emigration to the future pharmacists.