solvent, nature of catalyst, and especially by hydrogen-ion concentration. Pseudocodeine can thus be reduced in excellent yield to a new non-phenolic dihydropseudocodeine.2. The degradation of dihydropseudocodeine to dihydro-e-methylmorphimethine, and conversion of the latter to tetrahydro-e-methylmorphimethine is described. The preparation of tetrahydro-e-methyl-morphimethine through extension of the special hydrogenation method to e-methylmorphimethine has been accomplished.3. The degradation product from tetrahydropseudocodeine is correctly described and its relationship to hexahydro-e-methylmorphimethine established.
University, Virginia
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