In Fruchtwasser normaler und pathologischer Schwangerschaften wurden die Enzymaktivitäten von Lactat-und Malatdehydrogenase, alkalischer Phosphatase, saurer Phosphatase, Aspartat-und Alanintransaminase, Glucose-6-phosphat-Dehydrogenase, Leucinaminopeptidase, -Amylase und Cholinesterase gemessen. In normalem Fruchtwasser sind im wesentlichen Lactat-und Malatdehydrogenase, alkalische Phosphatase, -Amylase und Aspartattransaminase zu finden, die übrigen Enzyme sind nur in Spuren vorhanden. Bei Erythroblastosen infolge Rh-Inkompatibilität und bei Schwangerschaften mit Placenta-Infarkten stimmen die Mittelwerte der Aktivitäten mit denen im normalen Fruchtwasser überein. Bei mekoniumhaltigem Fruchtwasser ist die alkalische Phosphatase stets erhöht. Mit dieser einen Ausnahme besteht kein Zusammenhang zwischen dem Zustand des Kindes und der Aktivität der untersuchten Enzyme.
The enzymes of amniotic fluidMeasurements were made of the enzymatic activity of lactate and malate dehydrogenase, alkaline phosphatase, acid phosphatase, aspartate and alanine transaminase, glucose-6-phosphate dehydrogenase, leucine aminopeptidase, -amylase and cholincsterase in amniotic fluid obtained from normal and pathological pregnancies. In normal amniotic fluid the chief enzymes are lactate and malate dehydrogenase, alkaline phosphatase, -amylase and aspartate transaminase, the remaining enzymes being present in traces only. In erythroblastosis resulting from Rh-incompatibility and in pregnancies with infarcted placentas the mean values of the enzyme activities correspond to those of normal amniotic fluid. In amniotic fluid containing meconium the alkaline phosphatase is always incieased. With this one exception there was no relationship between the condition of the child and the activity of the above enzymes.
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