Industrialization is a major promoter of any nation's economy; it is not without detrimental effects on our immediate environment. Human exposure to various pollutants discharged into the environment may lead to serious health challenges. In the same vein, discharge from the combustion of fossil fuel contributes a great deal to the environmental pollution. The resulting quest for a clean and sustainable environment has spurred myriads of research into advantageous utilization of waste biomass in industrial wastewater treatment and environmentally friendly/alternative energy. Similarly, diverse waste materials have been adopted as sources of important phytochemicals with different medicinal applications. This chapter focuses on the application of waste biomass in environmental remediation, curative medicine, and clean/alternative energy.