The 17 days subcronic anakinetic stress induced to white Wistar rats by immobilization and darkness has determined TGO, cholesterol and triglycerides values increase, and serum creatinine decreases. Lamium album vegetable extract administration significant increases triglycerides and GOT values and decreases serum creatinine. Administration of both L. album and L. purpureum extracts, in terms of exposure to anakinetic stress, has resulted in a significant increase of the liver transaminases and triglycerides level, decrease of cholesterol and rise of serum creatinine levels. Administration of Lamium purpureum (LP group) vegetable extract has induced the increase of triglyceride values and decrease of cholesterol and serum urea levels. In the SLA group, there was an increase in the red blood cells (RBCs), hematocrit and platelet number, vs. the control group. It has also experienced an increase of the platelets in other treated groups. In the SLP group was noted an increase in the RBCs, hematocrit and platelet number vs. the control group and the decrease in the number of lymphocytes. In conclusion, the vegetal extracts of L. album and L. purpureum (20 mg/100 g b.w.), induced protective modulatory effects on the dynamics of the entire set of functional analyzed parameters.

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In this study we tried to see how (1:1 and 3:1) lingonberry extract act as protective agents of the myocardium and blood pressure in toxicosis induced by paracetamol in rats. Experiments were made on white female Wistar rats, weighing 135 ± 20 g which were divided into 6 groups of 7 animals each: control group (C); Paracetamol treated group (P) -75 mg acetaminophen/100 g bw for 10 days. 1:1 lingonberry hidroalcoholic treated group (Lha), (200 mg/100 g bw (80 µg benzoic acid/100 g bw) for 15 days. 3:1 lingonberry dried extract group (Ld), 100 mg/100 g bw (112 µg benzoic acid/100 g bw), for 15 days. P+Lha (PLha) and P + Ld (PLd) treated group. Blood pressure increases following administration of paracetamol and decreases under treatment with lingonberry extract, more obvious to 3: 1 lingonberry dried extract. Administration of Paracetamol, lingonberry extracts used simple or in combination with Paracetamol does not affect the myocardium histological structure. Histoenzimological there is a slight decrease of SDH activity in the groups P and PLd and an increase in Lha group. CyOx activity is increased in Lha and Ld group. The dried lingonberry extract has no apparent action on the myocardium instead has antihypertensive properties more obvious than the lingonberry alcoholic extract.