Twenty-five grams (0.15 mole) of XIV was refluxed with 42 g. of sodium hydroxide, dissolved in 350 ml. of water, for 24 hours. During this time ammonia was given off. The solution was then acidified with concentrated hydrochloric acid and refluxed for five hours more.The mixture was then filtered and extracted three times with ether, dried and distilled to yield 8 g. of -ethoxy-Y-valerolactone, b.p. 127-129°( 14 mm.), »26d 1.4419, yield 36%.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.