In the testicles, the expression of Angiotensin-Converting Enzyme 2 receptors makes it more susceptible to infection by Sars-CoV-2 and, therefore, to male infertility with significant health problems for the patient. Therefore, this study aimed to analyze the clinical pathophysiology and the mechanisms involved in the genesis of male infertility from COVID-19, through the critical analysis of the main scientific evidence on the subject presented so far. From an integrative review of the literature containing 30 studies selected using inclusion criteria in the period 2020-2021, the direct and indirect impacts on male fertility in pathophysiological and psychosocial terms were observed in this study, in addition to therapeutic options, guidelines host and efficient semiological approach. Thus, the impact of the pandemic, even after one year, is immeasurable. Additional studies to reveal the real consequences and the mechanism by which the disease can affect male fertility are still needed. It is essential to pay more attention to male genital exams in patients with COVID-19. The psychobiological consequences of the pandemic in infertile patients should not be underestimated.

The rapid spread of coronavirus disease (COVID-19) worldwide urges the need for studies on the illness and its management. The COVID-19 infection leads to hypercoagulation due to inflammatory cytokine release and D-dimer increase in critically ill patients, resulting in pulmonary thromboembolism (PE) and venous thromboembolism (VTE) evolving to sepsis and death. The study evaluated the currently existing evidence on heparin administration in patients with severe COVID-19. An integrative literature review was done by searching for scientific studies in the PubMed, Scopus, Embase, and Web of Science databases. The analyzed studies showed that heparin use in critically ill patients could efficiently prevent thrombotic events and reduce the exacerbated inflammatory process. However, further investigation on the effect on patients is still needed. The use of heparin in critically ill COVID-19 patients has been prescribed increasingly by doctors. But its use has not yet had its outcomes well established in the literature. Therefore, deeper investigations and new research development are needed to clarify potential beneficial effects.

SARS-CoV-2, a severe acute respiratory syndrome caused by Coronavirus 2, discovered in 2019 in China, is responsible for the current pandemic declared by the WHO since March 2020. The clinical syndrome caused by Covid-19 has a broad spectrum of severity. The most common clinical manifestations are fever, dry cough, dyspnea, fatigue, and anosmia. The virus binds to receptors for angiotensin-converting enzyme 2 (ECA2) and serine protease TMPRSS2 for protein S initiation, which are expressed not only in the lungs but also in the liver, colonic, esophageal and biliary epithelial cells. In this context, the liver is a potential target for COVID-19 infection. Liver damage occurs during the course and treatment of viral infection in patients with or without previous liver disease. Therefore, the characteristics of liver injury associated with COVID-19 were reviewed based on research related, in the context of the pandemic.

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Objective: to describe the physical characteristics and biological of the wires of more sutures used in surgical practice daily and their indications. Methods: Review was conducted of literature through to search in the databases Pubmed, Embase, Web of Science and Scopus. Results: were described data on the qualities of the ideal suture, general classification and descriptive, criteria for use and the physical and biological characteristics of absorbable sutures, wires, monofilaments and multifilamentary. Conclusion: it was possible to synthesize the current knowledge the respect of strands of suture, to be used by students of medicine, surgery residents, surgeons and its subspecialties.