Laryngospasm was more likely to occur in children with an active upper respiratory infection, children who were younger, children who were undergoing airway surgery, and children whose anesthesia were supervised by less experienced anesthesiologists. Understanding the risk factors and the magnitude of the likely risk should help clinicians make the decision as to whether to anesthetize children with upper respiratory infection.
pH-stat cardiopulmonary bypass management improves neurologic outcome with deep hypothermic circulatory arrest compared with alpha-stat bypass. The mechanism of protection is not related to hemodynamics, hematocrit, glucose, or brain temperature.
Cortical deoxygenation during hypothermic arrest was slower after pH-stat CPB. pH-stat bypass increased the prearrest ScO2 and arrest ScO2 half-life, to increase the cortical oxygen supply and slow cortical oxygen consumption. Improved cortical physiologic recovery after hypothermic arrest was suggested with pH-stat management.
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