A tremendous amount of information was published over the past decades in relation to the role of vitamins in various neoplastic diseases. In particular, several studies showed an inverse relationship between selected vitamins intake and cancer risk. In this review we will focus on the role played by vitamins in melanoma with particular regard to vitamin A, D, K, E and C. Given that vitamin supplementation is easy, convenient, and readily accepted by patients, in the future the use of vitamins in chemoprevention and therapy of melanoma could be encouraged if supported by pre-clinical and clinical evidence.

Welcome to EVALITA 2020! EVALITA is the evaluation campaign of Natural Language Processing and Speech Tools for Italian. EVALITA is an initiative of the Italian Association for Computational Linguistics (AILC, http://www.ai-lc.it) and it is endorsed by the Italian Association for Artificial Intelligence (AIxIA, http://www.aixia.it) and the Italian Association for Speech Sciences (AISV, http://www.aisv.it).This volume includes the reports of both task organisers and participants to all of the EVALITA 2020 challenges. In the 2020 edition, we coordinated the organization of 14 different tasks belonging to five research areas, being: (i) Affect, Hate, and Stance, (ii) Creativity and Style, (iii) New Challenges in Long-standing Tasks, (iv) Semantics and Multimodality, Time and Diachrony.The volume is opened by an overview to the EVALITA 2020 campaign, in which we describe the tasks, provide statistics on the participants and task organizers as well as our supporting sponsors. The abstract of the keynote speech made by Preslav Nakov titled "Flattening the Curve of the COVID-19 Infodemic: These Evaluation Campaigns Can Help!" is also included in this collection.Due to the 2020 COVID-19 pandemic, the traditional workshop was held online, where several members of the Italian NLP Community presented the results of their research. Despite the circumstances, the workshop represented an occasion for all participants from both academic institutions and private companies to disseminate their work and results and to share ideas through online sessions dedicated to each task and a general discussion during the plenary event.We carried on with the tradition of the "Best system across tasks" award. As in 2018, it represented an incentive for students, IT developers and researchers to push the boundaries of the state of the art by facing tasks in new ways, even if not winning.

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Melanoma is one of the most fatal cancers, and its incidence is increasing worldwide. Thanks to the better understanding of the molecular mechanisms involved in the pathogenesis of melanoma, recently new targeted agents have been developed. In this article, we review the current state of knowledge of clinical presentation, mechanisms, and management of the most common cutaneous side effects observed during treatment with targeted and immunological therapies approved for advanced melanoma. We include discussion of BRAF/MEK inhibitors and immune-checkpoint inhibitors, notably CTLA-4 and PD-1 inhibitors.