Conjugation of drugs with antibodies to surface endothelial antigens is a potential strategy for drug delivery to endothelium. We studied antibodies to plateletendothelial adhesion molecule 1 (PECAM-1, a stably ex-
INTRODUCTION: Brain metastases of breast cancer (BMBC) are the leading cause of brain malignancy and mortality in women with limited therapeutic options. Recent innovations by our group have demonstrated a novel BMBC-targeted therapeutic modality utilizing a human neural stem cell (hNSC) line approved by FDA for glioblastoma multiforme (GBM) therapy. Here we report a nano tracing strategy to expand the therapeutic scope of
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