Introduction. Preservation the health of the able-bodied population in the conditions of the delivery of progressive technologies, increasing the intellectualization of production, the formation of a new economic reality actualizes the introduction of modern technologies to ensure satisfactory working conditions, reduce the harmful effects of working environment factors, improve medical and preventive measures based on the creation of a health-saving environment at enterprises. The purpose of the study is to identify effective modern technologies for preserving the occupational health of employees of mining enterprises, aimed at improving working conditions, preventing occupational morbidity. Material and methods. A dynamic study of the working conditions and health status of mining industry workers was conducted. The data of statistical reporting of medical and sanitary units, periodic and preventive medical examinations, indicators of inpatient examinations of workers of the studied enterprises are presented. The domestic and foreign literature, the regulatory framework, and the data of our own research devoted to the development of modern technologies in occupational health are analyzed. Results. Priority production factors of health disorders have been identified, the structure of general somatic and occupational morbidity at mining enterprises has been studied. Developed preventive programs were implemented to optimize working conditions, promote a healthy lifestyle, prevent and rehabilitate occupational morbidity, and their effectiveness has been shown. Limitations. The study was conducted among workers of mining enterprises of working age on a representative sample. Conclusion. The use of modern technologies in occupational health, based on production and information security, timeliness of managerial decision-making, economic feasibility, becomes accessible and promising within the framework of the health-saving program of the working population. The introduction of progressive innovations contributes to high-quality expert, consultative, diagnostic and specialized assistance provided to the able-bodied population, personalization of preventive and rehabilitation measures of diseases caused by working conditions.

The article presents result of examination of 253 adolescents educating in institutions of secondary and secondary professional education. The approach is proposed substantiating expediency of including indicators of educational environment into listing of modifying factors of cardiovascular risk for adolescents on the basis of evaluation of degree of conjugation of rank sum on modifying factors with quantitative clinical functional and laboratory indicators.

Introduction. A significant level of dermatological morbidity requires consideration of the influence of external environmental factors on the development and progression of skin pathology. Purpose: to assess the structure of dermatological morbidity of the population exposed to harmful environmental factors, with the definition of priority for the children’s population. Objectives were to assess the structure of dermatological morbidity of the population exposed to harmful environmental factors, with the priority for the children’s population of the Mytishchi district of the Moscow Region. Material and methods: statistical data on the morbidity of the children’s population of the Mytishchi district of the Moscow Region and the dermatological department of the Institute of General and Occupational Pathology of the Federal Scientific Center of Hygiene named after F.F. Erisman of the Federal Service for Supervision in Protection of the Rights of Consumer and Human Wellbeing. Data on pollution by harmful environmental factors of the district, social and hygienic monitoring data in the Mytishchi district on pollution by harmful environmental factors, using mathematical statistics methods (correlation dependence, Student’s coefficient). Results. Residents of the Mytishchi district are exposed to adverse environmental factors, the children’s population is most susceptible to their influence. The greatest influence belongs to the pollution of atmospheric air and water. The most common skin pathology in children includes atopic dermatitis and eczema. Statistics of inpatient dermatological care for 2017-2019 in the profile department of the Institute of General and Occupational Pathology of the F.F. Erisman data indicate a similar distribution of skin pathology in the adult population. Conclusions. The obtained data require in-depth preventive examinations in organized children’s groups at regional enterprises to detect early forms of diseases and comprehensive hygienic preventive measures to improve the state of the environment in the Mytishchi district of the Moscow Region.

There are considered features of disorders of the immune response in chronic exposure to dust aerosols. The detected changes of indices of the immune status of employees of the dust dangerous occupations and patients with chronic dust pathology of the lungs were unidirectional in the character, which is probably caused by manifestations of nonspecific response of the immune system to the dust factor. The deterioration of cellular immunity, humoral immunity and cytokine profile predisposes to the occurrence of immunopathologic states, contributing to the development of caused by both worksite and occupation pathology.

The features of factual nutrition, indices of metabolism processes, immunity condition and adaptation potential of organism of adolescents of the Far North and middle zone of the Russian Federation are examined. The regional features of immunologic and biochemical indices of schoolchildren health condition. The analysis of correlation relationship between clinical laboratory indices of metabolism processes, immunity and antioxidant status of schoolchildren testifies condition of adaptive tension, more intensively expressed in schoolchildren of the Far North.