Persistent organic pollutants and heavy metals are damaging the environment. Crops and fields are destroyed by the seepage of heavy metals from untreated industrial waste. The burning and incineration of a variety of items also contributes to main and secondary emissions of pollutants. The excessive usage of Pesticides in Pakistan causes contamination, which effects the ecosystem. Although they increased life quality but also posed a significant health danger. The toxic properties of various pesticides and organic pollutants in Pakistani fruits was observed by exceeding the MRLs. The study aimed to stimulate discussion among Pakistan's stakeholders about the dangers and toxicity of pesticides, as well as prompt plans for environmental cleanup and more environmentally friendly farming. Due to ignorance, a sizable section of the populace is unaware of the issue of pesticide residues and their accumulation in the food chain. The major goal of the review is to record, evaluate, and examine the findings of earlier research on the levels of various pesticides in particular fruits from Pakistan. The results of the earlier investigations made it abundantly evident that more than 50% of the samples were contaminated with pesticides such as organophosphate, pyrethroid, and organochlorine.

Nanoparticles (NPs) are among the several NMs that can function as nano carriers because of their improved solubility, prolonged release, targeting potential, and aid in medication dosage reduction. Recent developments are discussed in this overview. To distribute medications, these small materials can locate the precise location in the body. In addition, they can lessen the negative effects of medications and assist patients in taking fewer pills while still achieving the same or better benefits. The development of nanoparticle medication delivery systems has been one of the most important research fields. This brief overview will concentrate on the traits that make for effective drug delivery systems based on nanoparticles as well as the numerous disease conditions where these nanoparticle systems have shown promise.