If you would like to write for this, or any other Emerald publication, then please use our Emerald for Authors service information about how to choose which publication to write for and submission guidelines are available for all. Please visit www.emeraldinsight.com/authors for more information. About Emerald www.emeraldinsight.comEmerald is a global publisher linking research and practice to the benefit of society. The company manages a portfolio of more than 290 journals and over 2,350 books and book series volumes, as well as providing an extensive range of online products and additional customer resources and services.Emerald is both COUNTER 4 and TRANSFER compliant. The organization is a partner of the Committee on Publication Ethics (COPE) and also works with Portico and the LOCKSS initiative for digital archive preservation. AbstractPurpose -A systematic literature review was performed to better understand the health promotion interventions proposed within the academic literature that aim to reduce the spread of sexually transmitted disease (STD) among Mexican migrants. Design/methodology/approach -The systematic review performed in this paper aimed to answer the research question: What interventions have been proposed within the academic literature to reduce the incidence of STD among Mexican migrants? A five-step decision tree was developed to review the 5,121 generated from the initial query. The final data set included 384 articles, 19 of which focussed on the target population. Findings -Results of the systematic review reflected eight themes: cultural, attitudinal, and contextual considerations, behavior modification, demographic factors, education, community mobilization, and access to services. The majority of themes suggest that structural level change is needed. Originality/value -Research on Mexican migrants in the USA is scant. Oftentimes research studies focus on "Hispanics" as a unit, neglecting the uniqueness of each individual subgroup. This paper addresses this limitation by focussing on Mexican migrants, a rapidly growing US population.