Objective: to describe the most frequent signs and symptoms of infection by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Methods: this is a narrative literature review carried out in April 2020; the search was performed on electronic databases and complemented with a manual review of the references of the selected papers and Brazilian Ministry of Health publications. Results: the spectrum of clinical disease was wide; fever, coughing and dyspnea were the most frequent signs/ symptoms, however, they may not be present, thus hindering case definition; gastrointestinal symptoms and loss of taste or smell have been reported among mild cases; dyspnea was frequent among severe and fatal cases. Conclusion: considering the scarcity of diagnostic tests and the diversity of symptoms, health services should use a sensitive case definition, in order to adopt appropriate surveillance, prevention and treatment actions.
Objetivo: descrever os sinais e sintomas mais frequentes na infecção pelo vírus da síndrome respiratória aguda grave coronavírus 2 (SARS-CoV-2). Métodos: revisão narrativa da literatura realizada em abril de 2020; a busca foi realizada em bases eletrônicas e complementada com revisão manual das referências dos trabalhos selecionados e das publicações do Ministério da Saúde do Brasil. Resultados: o espectro da doença clínica mostrou-se variado; Febre, tosse e dispneia foram os sinais/sintomas mais frequentes, no entanto, podem não estar presentes, dificultando a definição de caso; sintomas gastrointestinais e alteração de olfato ou paladar têm sido relatados entre casos leves; a dispneia foi frequente entre casos graves e com evolução ao óbito. Conclusão: considerando-se a escassez de testes diagnósticos e a diversidade de sintomas, os serviços de saúde devem utilizar uma definição de caso sensível, de forma a serem adotadas ações adequadas de vigilância, prevenção e tratamento.
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