Aims/Hypothesis. It was suggested that polyunsaturated n-3 fatty acids (n-3 PUFAs) could improve insulin sensitivity and have an anti-inflammatory effects in overall population. This study investigates a possible effect of n-3 PUFAs supplementation on the insulin sensitivity and some inflammatory markers; hence, patients with chronic renal failure (CRF) on maintenance hemodialysis (MHD) are presented with insulin resistance. Methods. This study explored the ratio between red blood cells (RBC) phospholipid long chain fatty acids (LC FAs) and components of metabolic syndrome (MeS) in 35 patients (mean age 54.50 ± 11.99 years) with CRF on MHD. Furthermore, the effects of omega-3 FA eight-week's supplementation (EPA+DHA, 2.4g/d) on the MeS features and inflammatory markers TNF-alpha, IL 6, and hsCRP were examined. Results. Supplementation increased EPA and DHA levels in RBCs (p = 0.009 for EPA and p = 0.002 for DHA). Total n-6 PUFAs: n-3 PUFAs ratio tended to be lower after supplementation (p = 0.31), but not significantly. Data revealed a significant decrease of saturated FAs (SFA) (p = 0.01) as well as total SFA: n-3 PUFAs ratio during the treatment (p = 0.04). The values of serum insulin and calculated IR index-IR HOMA were reduced after supplementation (p = 0.001 for both).There was a significant decrease in the levels of all inflammatory markers (p = 0.01 for TNF alpha, p = 0.001 for IL 6, p = 0.001 for hsCRP, and p = 0.01 for ferritin). In multivariate regression analysis, only the changes in n-6 PUFAs: n-3 PUFAs ratio independently contributed to 40% of the variance in IR HOMA. The impact of changes in PUFAs level in RBCs membrane phospholipid fatty acids on inflammation markers was also registered. The changes in n-6: n-3 PUFAs ratio independently contributed to 18% of the variance in TNF alpha. Conclusion. It was concluded that the EPA and DHA moderate dose administration in the patients with CRF on MHD had a beneficial effect on insulin resistance decrease. The anti-inflammatory effects of the supplemented PUFAs were also presented.

The dissolution of aluminum hydroxides from bauxite ores constitutes a key process in the aluminum industry. Generally, aluminum minerals in bauxites are present in the form of gibbsite, boehmite or diaspore. Usually, these mineral forms are mixed in bauxite as a boehmite-diaspore or a gibbsite-boehmite mixture with different weight ratios. The Al 2 O 3 recovery, as well as the kinetic parameters, during the Bayer leaching process of different bauxite types strongly depends on their mineralogical composition. In this paper an attempt was made to develop a mathematical model which enables calculation of the Al 2 O 3 recovery from boehmite-diaspore or gibbsite-boehmite bauxite based on kinetic parameters available for leaching the "pure" bauxite types (containing only diaspore, boehmite or gibbsite as the main alumina bearing mineral form) and the mineral composition of the bauxite mixture.Résumé -La dissolution des hydroxydes d'aluminium à partir de minéraux de bauxite constitue un procédé clé de l'industrie de l'aluminium. Généralement, les minéraux d'aluminium dans la bauxite sont présents sous forme d'hydrargillite, de boehmite ou de diaspore. Habituellement, ces formes minérales sont mélangées dans la bauxite en un mélange de boehmite-diaspore ou d'hydrargillite-boehmite, avec différents ratios en poids. La récupération de l'Al 2 O 3 , ainsi que les paramètres de la cinétique lors du procédé de lixiviation de Bayer de différents types de bauxite, dépend fortement de leur composition minéralogique. Dans ce document, on a essayé de développer le modèle mathématique qui rend possible le calcul de la récupération de l'Al 2 O 3 à partir de bauxite de boehmite-diaspore ou d'hydrargilliteboehmite, basé sur les paramètres cinétiques disponibles pour la lixiviation des types "purs" de bauxite (contenant seulement du diaspore, de la boehmite ou de l'hydrargillite comme forme minérale principale porteuse d'alumine) et sur la composition minérale de la bauxite mélangée.

Coronary artery disease (CAD) and myocardial infarction (MI) are recognized as leading causes of mortality in developed countries. Although typically associated with behavioral risk factors, such as smoking, sedentary lifestyle, and poor dietary habits, such vascular phenotypes have also long been recognized as being related to genetic background. We review the currently available data concerning genetic markers for CAD in English and non-English articles with English abstracts published between 2003 and 2018. As genetic testing is increasingly available, it may be possible to identify adequate genetic markers representing the risk profile and to use them in a clinical setting.

This paper presents the results of acidic leaching of kaolinite from the flotation waste of the RTB Bor copper mine, Serbia. The kaolinitic concentrate from the flotation waste contains 32% Al2O3. Kinetic investigations were conducted on the leaching of kaolinite roasted at 750°C for 60 min under air using H2SO4, HNO3 and HCl. Activation energies for the process were 74, 63 and 63.2 kJ mol–1 for sulphuric, nitric and hydrochloric acids, respectively. The kinetic function D3: [1 – (1 – α)1/3]2 = kt was chosen to describe the fractional conversion dependence on time and temperature. This enabled effective management of the leaching process to be carried out.

This paper presents the results of defining the mathematical model which describes the dependence of leaching degree of Al2O3 in bauxite from the most influential input parameters in industrial conditions of conducting the leaching process in the Bayer technology of alumina production. Mathematical model is defined using the stepwise MLRA method, with R2 = 0.764 and significant statistical reliability - VIF<2 and p<0.05, on the one-year statistical sample. Validation of the acquired model was performed using the data from the following year, collected from the process conducted under industrial conditions, rendering the same statistical reliability, with R2 = 0.759