The present study was undertaken to investigate the antioxidant and anti-glycation activity of lemongrass (C. Citratus)
leaves extract. The antioxidant activity was measured by hydroxyl radical and hydrogen peroxide scavenging activity and
chelating effect of ferrous iron. The anti-glycation activity was determined by inhibition of hemoglobin glycation method.
The results of this present studies showed that the C. Citratus leaves extract to have hydrogen peroxide and hydroxyl radical
scavenging activity, and chelating effect of ferrous iron activity. The results also showed that the C. Citratus leaves extract
to have anti-glycation activity. The result showed that C. Citratus leaves extract more effective in all activity, except for
hydrogen peroxide scavenging activity. The present study indicated that C. Citratus leaves extract showed a potential
antioxidant and anti-glycation activity.
The objectives of this study were to determine the involvement of Oxidative Stress (OS) in the pathogenesis of dengue hemorrhagic fever (DHF) through the analysis of oxidative stress Index (OSI). The levels of malondialdehyde (MDA), superoxide dismutase (SOD) and catalase (CAT) activity, and OSI were measured in 61 child dengue patients and (aged 6 months-18 years) with three different stages of DHF, i.e stage I, II, and III. The results show that the levels of MDA, SOD and CAT activity, and OSI significantly different between the group. The all parameters that investigated in this present study seems higher MDA level and OSI in the higher grade of DHF, except for SOD and CAT activity. From this result, it can be concluded that oxidative stress pathways might be involved in the pathomechanism of DHF and OSI might be used as a biomarker for OS and the severity in DHF patients.
In the present study antioxidant and antioxidant activity of some tropical fruits was evaluated. Antioxidants are compounds or molecules that can scavenging and prevent free radicals and reactive oxygen species that can caused a cell damage. Fruit was known as a source of antioxidant. South Kalimantan Indonesia, has a variety of fruit such as mentega, nangka, timun suri and kuranji. Study for evaluating the antioxidant levels and activity of those fruit were never been investigated. Thus, our study aim to measure the antioxidant levels and antioxidant activtity of those selected fruits. Ascorbic acid, lycopene, b-carotene levels and antioxidant activity of four selected tropical fruits was evaluated using spectrophotometer. The result of this studied suggest that the four selected tropical fruits is potential antioxidant because it contained ascorbic acid, b-carotene, lycopene and had effect of scavenging radical hydroxyl, hydrogen peroxide and chellating ferrous iron.
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