Considerable anthropization degree of environment during the modern period had determined a gradual sinking of ecological stability of geographical landscapes, especially given the predominance of agricultural landscapes which occupy 73.4% from total area of Republic of Moldova at present [1]. Land Cadastre data for Republic of Moldova (2000-2020) [2] and population level’s statistical data (2000-2019) [3] was used to obtain a few indicators that reflect the state of geographical landscapes (population density, naturality index and environmental changes index) and quantify the anthropic pressure on the geographical landscapes at the commune level. We had used the period of 2000-2020 as the reference period.