The aim of this study was to review research findings and information about chemical composition and application of bee drone brood homogenate for food purposes. As the world’s population grows, global warming and the impact of meat production on the ecosystem are increasingly being discussed. Various non-traditional sources of protein, such as insects and larvae, could replace traditional sources of meat protein in the future. Drone brood homogenate is obtained from honey bee drone larvae and is considered to be a very high value by-product of beekeeping. Scientific studies prove the prophylactic properties of drone brood homogenate to improve fertility and strengthen immunity against viral diseases. This product is rich in nutrients, amino acids, vitamins, minerals and hormones but a certain harvesting and processing technology is required to ensure that the product has a sufficient shelf life and an attractive appearance.