a b s t r a c tGlial choristoma is considered a developmental malformation characterized by brain heterotopias without connection to the central nervous system. In this article, we report a rare case of glial choristoma occurring on the dorsum of the tongue with cleft palate in a 3-month-old male infant. Complete surgical excision was performed prior to palatoplasty. There were no postoperative complications or evidence of recurrence after 5 years of follow-up.

: We describe our experience with a case of congenital epulis arising in both the maxillary and mandibular alveolar ridge, which showed spontaneous regression. Two distinct lesions were found in an 8-dayold newborn infant at the first medical examination: one was a sessile lesion on the maxillary alveolar ridge corresponding to the right upper deciduous canine, and the other was a pedunculated lesion on the mandibular alveolar ridge corresponding to the right lower deciduous lateral incisor. Because the patient did not have any problem with feeding using a nursing bottle or with breathing, we decided to perform follow-up observation.

Cleft of the soft palate (CSP) and the hard palate (CHP) are subtypes of cleft palate.Patients with either condition often have difficulty with speech and swallowing.Nonsyndromic, cleft palate isolated has been reported to be associated with several genes, but to our knowledge there have been no detailed genetic investigations of CSP.We performed a genome-wide linkage analysis using an SNP-based microarray platform and successively using microsatellite markers in a family where six members, across three successive generations, had CSP. A maximum LOD score of 2.408 was obtained at 2p24.2-24.1 and 2p21-p12, assuming autosomal dominant inheritance.Our results suggest that either of these regions is responsible for this type of CSP.Keywords: cleft of the soft palate/genome-wide linkage analysis/submucous cleft palate 4