OBJECTIVE: Obstetric problems have detrimental effects on both pregnancy and newborn. We aimed to examine the relationship between pregnancy complications and newborn morbidities. STUDY DESIGN: The newborns admitted to the neonatal intensive care unit between September 2019 and August 2022 were included in this retrospective cross-sectional study. Antenatal morbidities and neonatal complications including low APGAR-score (<5), bronchopulmonary dysplasia, early neonatal sepsis, and early neonatal death were evaluated. Pearson-χ2 cross-tabs were used to compare two variables. A p-value <0.05 was determined statistically significant. RESULTS: Among the 686 infants analyzed, 94 (13.7%) had early neonatal death, 264 (38.5%) had bronchopulmonary dysplasia, 259 (37.8%) had early neonatal sepsis, and 424 (61.9%) had feeding intolerance. Early neonatal sepsis was observed significantly higher in newborns whose mothers had urinary tract infection in the last two weeks (p<0.001), preterm premature rupture of membranes (p=0.006), or clinical chorioamnionitis (p<0.001). Early neonatal death was found significantly higher in pregnancies with preeclampsia (p<0.001), preterm premature rupture of membranes (p<0.001), clinical chorioamnionitis (p<0.001), or small-for-gestational-age (p<0.001). Preeclampsia and magnesium neuroprophylaxis were found significantly higher in neonates with feeding intolerance (p<0.001). Backward: LR logistic regression analysis based on early neonatal sepsis risk revealed that birth week, preterm premature rupture of membranes, clinical chorioamnionitis, small-for-gestational-age, and urinary tract infection were significant parameters affecting the risk of early neonatal sepsis (p<0.05). CONCLUSION: Preventing premature births and cautious management of pregnancy complications may be helpful in reducing adverse neonatal outcomes. Early detection of high-risk pregnancies and transfer to a tertiary center may be helpful to improve neonatal outcomes.

Objective: Uterine corpus involvement was demonstrated radiologically or diagnosed by endometrial biopsy in the previous reports. Thus, there are few studies that detect uterine corpus involvement in radical hysterectomy specimens. This study was designed to investigate the factors that influence uterine corpus involvement in surgically treated cervical cancer patients. Materials and Methods: A total of 269 patients with clinical early-stage (stageIB1-IIA2) cervical cancer who underwent radical hysterectomy and pelvic-paraaortic lymphadenectomy at Zekai Tahir Burak Women's Health Training and Research Hospital and Ankara Bilkent City Hospital between January 2008 and August 2021 were recruited, and their clinicopathologic data were extracted from their patient files or the hospital's electronic database. Results: Uterine invasion was positive in 102 (37.9%) patients. Tumor size of patients was ≤20 mm in 66 (24.5%) patients and >40 mm in 82 (30.5%). Parametrial invasion was detected in 44 (16.4%) patients. In the multivariate analysis; tumor type (adenocancer vs. other tumor types) (HR: 8.94; 95% CI: 3.569–22.401; p35 mm vs. ≤35 mm) (HR: 2.34; 95% CI: 1.234–4.440; p=0.009) depth of stromal invasion (>1/2 vs. ≤1/2) (HR: 6.63; 95% CI: 2.205–19.952; p

Objective: Urinary incontinence is defined as urinary incontinence that is a social or hygienic problem and can be objectively demonstrated. It is aimed to compare tolterodine, trospium chloride and solifenacin treatments, and its side effects on patients who have complaints of pure urinary and mixed incontinence. Material and Method: Totally 98 patients, who applied to Ankara Etlik Zubeyde Hanım Gynecology Training and Research Hospital, Urogynecology Outpatient Clinic between November 2009 and October 2010 with compliants of urinary incontinence and met the criteria to participate in the research, have been included in this study. Results: A significant improvement in each three of the drug group at third and six months was determined. Solifenacin is generally more effective than the other two treatments. When total values of UDI-6 (Urinary Distress Inventory) survey is analysed, it is seen that each of three antimuscarinic drug group ensured improvement on symptoms at the end of the third month as not to be different from the improvement at the six month. Each three antimuscarinic drug group has a significant therapeutic effect on the IIQ-7 (Incontinence Impact Questionnaire) survey which questions the life quality. Whereas complaints of constipation was seen more at patients that use tolterodine and trospium chloride, there was not a significant difference despite a slight increase in the solifenacin group (p>0.05). It is determined that solifenacin caused desert mouth less than the other two drug groups Conclusion: Tolterodine, trospium chloride and solifenacin as anticholinergic drugs meaningfully reduced the activity of bladder and increased the quality of life. Drug therapy provided an effective and efficient improvement on incontinence.

Objective: Cytomegalovirus (CMV) is the most common viral infection. In this study, we discussed the results of pregnant women who underwent antenatal CMV screening in a tertiary center and the value of CMV antenatal screening. Methods: For this retrospective study, the data of pregnant patients with antenatal CMV screening test results between 2019 and 2022 were obtained from hospital records. CMV immunoglobulin M (IgM), CMV IgG, anti-IgG avidity test results, amniocentesis, CMV polymerase chain reaction (PCR), and the outcome of the babies were recorded. Results: A total of 31,912 CMV IgM and 26,969 CMV IgG tests were performed. CMV IgG seropositivity was observed in 78.99% of pregnant women, and 0.09% of the pregnant women were confirmed to have a positive CMV IgM test result. Pregnant women with positive IgM accompanying low avidity were referred to perinatology clinics for detailed ultrasonography and amniocentesis. Only 3 of the 44 pregnant women who underwent amniocentesis were confirmed to have positive CMV PCR testing. Conclusions: CMV screening should be preserved for pregnant women with ultrasonographic findings at high risk of congenital CMV infection.