A case of systemic amyloidosis presenting as a fast growing goitre is reported. There was neither clinical nor biochemical evidence of hepatic, cardiac or renal involvement, in contrast with previously reported cases. Despite large deposits of amyloid in the thyroid the clinical and biochemical studies demonstrated a normal thyroid function.
Plasma ghrelin levels could be decreased in obese patients as a compensatory mechanism to their nutritional state, but our results do not support the postulated beneficial role of ghrelin in the 1-year weight loss after BPD. They rather suggest that weight loss somehow stimulates ghrelin secretion, even in the absence of part of the stomach.
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