Background Evaluating 2-years implant loss and marginal bone loss in patients with hereditary coagulopathies, comparing with a healthy control group. Material and Methods 37 implants in 13 patients (17 haemophilia A, 20 Von-Willebrand disease) versus 26 implants in 13 healthy patients. Data measured through Lagervall-Jansson index (after surgery, at prosthetic loading, at 2 years). Statistics: Chi-square, Haberman’s, ANOVA, Mann-Whitney-U. Significance p <0.05. Results Haemorrhagic accidents in 2 coagulopathies patients (non-statistical differences). Hereditary coagulopathies patients suffered more hepatitis ( p <0.05), HIV ( p <0.05) and less previous periodontitis ( p <0.01). Non-statistical differences in marginal bone loss among groups. 2 implants were lost in the hereditary coagulopathies and none in the control group (non-statistical differences). Hereditary coagulopathies patients had longer ( p <0.001), and narrower implants ( p <0.05) placed. 43.2% external prosthetic connection in hereditary coagulopathies patients ( p <0.001); change of prosthetic platform more frequent in control group ( p <0.05). 2 implants lost: external connection ( p <0.05). Survival rate 96.8% (hereditary coagulopathies 94.6%, control group 100%). Conclusions Implant and marginal bone loss at 2 years is similar in patients with hereditary coagulopathies and control group. Precautions should be taken on the treatment for hereditary coagulopathies patients, through prior haematological protocol. Implant loss only occurred in in a patient with Von-Willebrand´s disease. Key words: Dental implants, inherited coagulation disorders, haemophilia A/B, Von Willebrand disease, marginal bone loss.