An improved diagnosis algorithm has been established. Group 2 allergens seem to have a leading role in mite allergy, but as group 1 sensitization could be species-specific in some patients and its prevalence is higher in children, an adequate balance on major mite species and major allergens must be consider in the design of mite allergy vaccines.

Tp was the second more frequent storage mite in the house dust samples from patients allergic to Dpt in Huelva. However, only half of the exposed patients were sensitized to Tp and the majority inhabited in urban areas. No significant correlation were found between IgE-antibody levels to Dpt and Tp. The RAST inhibition studies confirmed the low cross-reactivity between these mites.

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