Modifications of the Cohn techniques are the methods of choice for the preparation
of dilute albumin (PPS) and ϒglobulin solutions on an industrial scale. For the manufacture
of refined albumin solutions, however, considerable labour and material is saved if
crude, ethanol-precipitated fractions are heated in the presence of stabilisers in order to purify
the albumin. The technique is simple and cheap, and yields a safe product of high quality.
Bacterially contaminated and highly haemoglobinized plasma can be successfully heat-treated.
Modifications of the Cohn techniques are the methods of choice for the preparation fo dilute albumin (PPS) and gamma-globulin solutions on an industrial scale. For the manufacture of refined albumin solutions, however, considerable labour and material is saved if crude, ethanol-precipitated fractions are heated in the presence of stabilisers in order to purify the albumin. The technique is simple and cheap, and yields a safe product of high quality. Bacterially contaminated and highly haemoglobinized plasma can be successfully heat-treated.
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