There exists a disconnect between the European psoriasis treatment guidelines and the various CEE country-specific biologic coverage eligibilities. The cost of biologic therapy for psoriasis is not solely and directly responsible for the different use rates amongst the CEE countries. Psoriasis may not be perceived by all payers as a serious disease that can be successfully treated in a cost-effective manner.

Our study demonstrate that wintertime primary osteosynthesis increases the risk of conversion surgeries. The results may help improving the outcome of primary fixation of femoral neck fractures.

In order to achieve both health benefit and cost-effectiveness it is crucial that biological therapy is initiated early enough in the course of the disease, after the failure of non-biological therapies. Health authorities in close collaboration with clinical decision-makers should ensure that early detection of the disease and early initiation of appropriate therapies-including non-biological and biological therapies-are carried out in the health care systems.

1540.59 days). CONCLUSIONS: Higher age and having arthroplasty were associated with increased risk of secondary hip fracture in elderly women. The higher risk of secondary hip fracture in patients with hip arthroplasty could be explained by their longer survival after primary treatment. Further analyses of risk factors are needed to elaborate effective prevention strategies for secondary hip fractures.

rating the videolaparoscopy technique into SUS. Survey about the number of hospitalization and expenditures related to bariatric surgeries effectuated in Brazil in the period between 2008 and 2012. METHODS: Search, analysis and critical scientific literature usage based on Medline, Pesquisa Saúde and Rebrats (The Brazilian Network for Health Technology Assessment). A priority was attributed to Brazilian studies and studies financed by Department of Science and Technology (DECIT) of the Ministry of Health of Brazil. Data acquisition of expenditures related to bariatric surgery in the database of the IT Department of SUS (DATASUS). RESULTS: There have been no observable differences between laparotomical and laparoscopical methods in such terms as mortality and weight loss. But there have been significant differences in the quality of life of the patient and internalization time. The studies financed by DECIT show that the cost of the surgery varies according to the access route. The average expenditure for videolaparoscopy was US$12,448.00 compared to US$4,911.00 for the conventional surgery. Data of DATASUS indicates that the number of hospitalization for bariatric surgery paid by SUS was 16.785. In this period an increase of more than 68% was observed. The aggregate value of the expenditure in this field was US$44,116,330.031 for these years. CONCLUSIONS:The results show that the number of bariatric surgery has increased significantly in the last years. Therefore it's necessary to conduct a cost-benefit analysis in the standpoint of the SUS. This analysis should consider the implications to the quality of live of patients when evaluating videolaparoscopy bariatric surgery way.OBJECTIVES: Chronic kidney disease (CKD) and end-stage kidney disease are wellestablished risk factors for early mortality and morbididy in patients with coronary A403