No abstract

¼ 0.03) were significant predictors of residual disease. However, lesion's size, biochemical scoring, prior TACE, multifocality, tumor pathology, segmental location and nearby vasculature did not have an impact. Conclusions: Subcapsular location, degree of cirrhosis, presence of NASH, age and elevated BMI were independent factors associated with higher likelihood of residual disease. This high rate of recurrence after MWA in the HCC subset, warrants further investigation into factors predicting early recurrence and potential adjuvant therapies.

Additional analysis found that for every year increase between images analyzed, ML sac dimension increased by 0.2 mm (SE ¼ 0.097, p ¼ 0.037). Conclusions: Untreated PAVM feeders grew very slowly if at all in the near-decade span of this study, and any demonstrated growth was minimal. These findings challenge the current recommendation of 3-to 5-year CT follow-up.

Patients consisted of 56 males (79%), mean age of 62 (r, 37-86), with each patient undergoing 1-5 TACE sessions. Endpoints included target lesion response and overall treatment response, as defined by the mRECIST criteria, as well as patient survival. Preprocedural liver MRI was reviewed for presence of arterial feeder. Multilevel logistic regressions and Cox regressions were used to assess the effects of arterial feeder presence on treatment response and patient survival, respectively, adjusting for other covariates. Results: Overall treatment response (complete and partial) was seen in 56% of TACE treatments in 69% of patients. Arterial feeder was present on preprocedural MRI in 36% of TACE sessions. The presence of arterial feeder on pre-TACE MRI led to better target lesion response (OR ¼ 20.43, p ¼ 0.0001) and overall treatment response (OR ¼ 14.91, p<0.0001). Mean survival for all patients was 21.8 months (r, 1.3-54.8). Advanced age (HR ¼ 1.05, p ¼ 0.046) and increased tumor size (HR ¼ 1.15, p ¼ 0.002) were associated with reduced patient survival after TACE. The presence of arterial feeder also trended towards increased survival (HR ¼ 0.41, p ¼ 0.0696), although this relationship did not reach statistical significance. Conclusions:The presence of an arterial feeder on pre-TACE MRI predicts both target lesion response and overall treatment response after TACE. Further research to validate if presence of arterial feeder can be a non-invasive marker of tumor response and improved patient survival is warranted. Abstract No. 520Survival analysis using albumin-bilirubin grade for patients treated with drug-eluting bead transarterial chemoembolization (DEB-TACE) for hepatocellular carcinoma