Polypoidal choroidal vasculopathy is not rare in Caucasian patients presenting with occult choroidal neovascularization. The fundus abnormalities seen in such eyes overlap with the typical manifestations of AMD. Whereas the prognosis after photocoagulation of peripapillary polypoidal lesions appears to be relatively good, it is more guarded for macular or arcade lesions.

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The choroidal circulation was studied in 27 eyes with choroidal neovascular diseases by means of fluorescein and indocyanine green (ICG) angiography. In 10 of the cases the disciform response was seen to be associated with either watershed zones of the choroidal circulation or with areas of choroidal circulatory disturbance. This is consistent with the theory that hypoxic regions of the choroid are the underlying cause of macular disciform response.

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