No abstract

Osteocalcin and the bone-specific fraction of alkaline phosphatase were determined in sera of 50 kidney transplant recipients. Compared to the upper limit of the reference intervals (97.5 percentiles), the bone-specific alkaline phosphatase was more often increased than osteocalcin (25 vs. 5). There was only a weak correlation between the two analytes (r s = 0.306). it was concluded that osteocalcin and the bone fraction of alkaline phosphatase do not identically reflect the bone formation in patients after kidney transplantation. The determination of bone fraction of alkaline phosphatase was recommended to follow up the bone metabolism in these patients.