Pyridine derivativesPyridine derivatives R 0380 Synthesis and Biological Activity of Cyanopyridine, Isoxazole and Pyrazoline Derivatives Having Thymol Moiety. -A variety of the title thymol derivatives (V), (VI) and (VII) are synthesized via condensation reactions of chalcone derivatives (III). The products display moderate to good antimicrobial activities. -(DESAI, J. M.; SHAH*, V. H.; Indian J. Chem., Sect. B: Org. Chem. Incl. Med. Chem. 42 (2003) 2, 382-385; Dep. Chem., Saurashtra Univ., Rajkot 360 005, India; Eng.) -M. Kowall 22-137
Pyrazole derivatives
Pyrazole derivatives R 0180Synthesis and Antimicrobial Profile of 5-Imidazolinones, Sulfonamides, Azome-
thines, 2-Azetidinones and Formazans Derived from 2-Amino-3-cyano-5-(5'-chloro-3'-methyl-1'-phenylpyrazol-4'-yl vinyl)-7,7-dimethyl-6,7-dihydrobenzo(b)thiophenes. -Fifty title compounds of type (III), (V), (VII), (IX), and (XI) are prepared and tested for their antimicrobial activity. Some compounds show antimicrobial activities comparable to standard drugs. -(DESAI, J. M.; SHAH*, V. H.; Indian J. Chem., Sect. B: Org. Chem. Incl. Med. Chem. 42 (2003) 3, 631-635; Dep. Chem., Saurashtra Univ., Rajkot 360 005, India; Eng.) -M. Bohle 24-100
Synthesis, structural characterization, and biological activity studies of benzo[b]thiophene derivatives containing b-lactam nucleus are described. Cycloaddition of azomethines (4a-j) to in situ-generated ketenes from 2,4-dichlorophenoxyacetic acid, in the presence of triethylamine and benzenesulfonyl chloride afforded the title compounds (5a-j). The stereochemical course of reaction depends on both the substituents on the ketenes as well as on the imines. The mechanism for the formation of cis/ trans derivative is presented.
Synthesis, Spectral Studies and Biological Profile of Pyrazolines [cf. (VII)], Isoxazoles [cf. (VI)], Cyanopyridines [cf. (V)] Having Phenothiazine Moiety. -(DESAI, J. M.; SHAH*, V. H.; Indian J.
Synthesis and Biological Activity of Substituted Benzo[b]thiophenes, Benzothieno[2,3-d]pyridines, Benzothieno[2,3-d]pyrimidines, and Benzothieno[2,3-d]pyrazoles.-Among a series of title compounds the derivatives (V), (VIII), and (X) show antibacterial activity against E. coli comparable to that of ampicilline or chloramphenicol.-(DESAI, J. M.; SHAH, V. H.; Indian J.
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