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A simple chalcone based fluorescent chemosensor 1, capable of detecting Fe3+ in aqueous media, has been designed and synthesized by the condensation of 3-formyl-2-hydroxyquinoline and acetophenone.

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A binaphthyl derived fluorescent probe (S)-1 was developed for dual channel detection of Ni 2+ and Al 3+ ions. The sensing of Ni 2+ and Al 3+ ions takes place by two pathways: (i) fluorescent turn-on response via the blocking of the photoinduced electron transfer process and (ii) red-shifted fluorescent enrichment via the intramolecular charge transfer process. All these findings were supported by NMR, mass spectrometry, and theoretical studies. In addition, sensing of Al 3+ ions was successfully applied into live cells for bioimaging studies and logic gate applications.

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