Vitrectomy is an acknowledged method in the therapy of chronic uveitis and its complications. We analysed the functional results after vitrectomy of 106 patients (121 eyes). In more than 61% of the patients, the visual acuity improved more than one line. There is less glare, and stereoscopic vision is better. In 10% of the patients, the follow-up was complicated by a retinal detachment; in contrast, a primary retinal detachment was the indication for the vitrectomy in 19%. Our study shows that vitrectomy helps reducing the frequency of recurrence of uveitis and the intensity of drug therapy.