!Aim: Endometriosis is a chronic gynaecological disorder with manifold symptoms and psychosocial effects on the lives of affected women. The prevalence of endometriosis is estimated to be up to ten percent of women of reproductive age. As a result of its unclear aetiology, only limited treatment options are available. The treatment and care of affected women is therefore a challenge for their doctors. There is a need for healthcare services to provide affected women with support to cope with the disorder better. The aim of the study was to identify supporting and inhibiting factors on disease management to develop new support ideas. Materials and Methods: The results are based on a content analysis evaluation of text responses from 135 women with confirmed endometriosis. Open questions about disease management were posed in a patient questionnaire. A classification system was developed according to Mayrings Qualitative Content Analysis, which allowed the main topics to be identified and summarised qualitatively using a quantitative intermediate step.Results: Social support, treatment, as well as professional and healthcare system performance were found to be particularly supportive by patients. However, when questioned about inhibiting factors, healthcare system professionals and their performance were most commonly criticised. Just over 50% of women expressed their criticism of doctors. Quality of care and empathy towards the patients were especially criticised. There is also a need for improvement with regard to communication and general support from doctors. The results illustrate the importance of doctors for women affected by endometriosis, but make it clear that there is a great need for improvement with regard to the profession. Zusammenfassung

Abstract:The aim of the current study was to estimate total intake and dietary sources of eicosapentaenoic acid (EPA), docosapentanoic (DPA), and docosahexaenoic acid (DHA) and compare DHA intakes with the recommended intakes in a cohort of pregnant and lactating women. Twenty-four-hour dietary recalls and supplement intake questionnaires were collected from 600 women in the Alberta Pregnancy Outcomes and Nutrition (APrON) cohort at each trimester of pregnancy and 3 months postpartum. Dietary intake was estimated in 2 ways: by using a commercial software program and by using a database created for APrON. Only 27% of women during pregnancy and 25% at 3 months postpartum met the current European Union (EU) consensus recommendation for DHA. Seafood, fish, and seaweed products contributed to 79% of overall n-3 long-chain polyunsaturated fatty acids intake from foods, with the majority from salmon. The estimated intake of DHA and EPA was similar between databases, but the estimated DPA intake was 20%-30% higher using the comprehensive database built for this study. Women who took a supplement containing DHA were 10.6 and 11.1 times more likely to meet the current EU consensus recommendation for pregnancy (95% confidence interval (CI): 6.952-16.07; P < 0.001) and postpartum (95% CI: 6.803-18.14; P < 0.001), respectively. Our results suggest that the majority of women in the cohort were not meeting the EU recommendation for DHA during pregnancy and lactation, but taking a supplement significantly improved the likelihood that they would meet recommendations.

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Es wird eine Methode zur eindimensionalen dünnschichtchromatographischen Trennung und quantitativen Auswertung der Serumlipidfraktionen beschrieben. Dieses Verfahren ermöglicht Aussagen über den Gehalt an Phospholipiden, Triglyceriden, Monoglyceriden, freien Fettsäuren, freiem Cholesterin und Cholesterinestern und genügt damit den Fragestellungen der Routinediagnostik. Die Ergebnisse von 20 Paralleluntersuchungen zu chemisch-analytischen Bestimmungen einzelner Lipidfraktionen werden verglichen und diskutiert. Determination of serum lipids by quantitative one dimensional thin layer chromatographyA method is described for the one dimensional thin layer Chromatographie separation and quantitative evaluation of serum lipid fractions. The metho4 gives values for phospholipides, triglycerides, monoglycerides, free fatty acids, free cholesterol and cholesterol esters, and it therefore satisfies the requirements for routine diagnosis. The results from 20 parallelstudies on the analytical chemical determination of individual lipid fractions are compared and discussed.Dünnschichtchromatographische Lipidtrennungen haben auch für die klinische Diagnostik zunehmend an Bedeutung gewonnen. Zahlreiche Autoren konnten bisher über Gruppentrennungen verschiedener Serumlipide (l-5) und weitergehendere Differenzierungen (6-13) berichten. Demgegenüber erforderten quantitative Auswertungen eine aufwendige Kombination mit kolorimetrischen (9, 14-16), spektrophotometrischen (17, 18) oder radiometrischen (19) Verfahren. Erst photodensitometrische Bestimmungen (20-22) und eine vereinfachende Methode durch direkte Extinktionsmessungen (23) konnten den apparativen und zeitlichen Aufwand vor allem bei der Bestimmung wenig polarer Lipide entscheidend reduzieren. In dieser Arbeit soll erstmals über eine analoge quantitative eindimensionale Trennung von Serumlipiden im Vergleich zu chemisch-analytischen Bestimmungen einzelner Lipidfraktionen berichtet werden. Methodik