The following pathogenic bacteria and fungi are used to evaluate the antimicrobial activity of the newly synthesized compounds. Pseudomonas aurginosa (P. auroginosa, ATCC 27853), Staphylococcus aurueus (S. aurueus, ATCC 25923), Bacillus subtilus (B. subtilus, ATCC 6633), Candida albicans (C. albicans, isolated from a local hospital and was inoculated on a chocolate agar plate and grown at 37°C for 48 h) and Escherichia coli (E. coli, ATCC 29522) cultured on Mueller Hinton agar.