CHARLES 11. GKCBEK, JK. AN) JACK M. MOSIEK.~ ( K i t h assistance of Charles Loflont ) Lilly Laboratory for Cliniriil ResParcIa, 1ndiannpoli.s General Hospital, Iiidinm7poh. Inti.Phenaglycodol ( 2 -p-chlorophen y 1-3 -methyl-2, 3-butanediol) has, by rat screening methods. anticonvulsant and sedative properties.: These authors report the following oral doses for rats: electroshock ED,,, t SE = 63.0 6.6 mgTkg; metrazol ED:,, t SE = 45.1 t 7.7 mg/kg, ataxia EDso t SE = 86.5 t 6.1 : hypnotic ED5,, L -SE = 165.7 t 16.6 me, kg; and the LD;n t SE = 832.4 t 37.5,
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