Background: The Henoch-Schönlein Purpura (HSP) orIgA vasculitis is the most common vasculitis of childhood and may occur with renal involvement, with hematuria and / or proteinuria, and may cause severe and non-reversible sequelae.Objectives: To establish the profile of patients with renal involvement due to IgA vasculitisand to describe our experience with the use of azathioprine to treat patients with nephritis. Methods: Clinical data were retrospectively collected from medical records of patients with IgA vasculitiswho attended the pediatric rheumatology unit between 1995 and 2017. Patients were separated into two groups based on whether or notthey weretreated with non-glucocorticoid immunosuppressants. Results: From the178 patients with IgA vasculitis,nephritis was found in67 patients (37.6%), 13 of whom receivedtreatment with non-glucocorticoid immunosuppressants. Ten patients responded well to azathioprine and 1 patient to cyclosporine. Forty patients received oral glucocorticoids, whilst 16received intravenous glucocorticoids. Conclusion: Azathioprine may be beneficial in the treatment of IgA vasculitis with renal involvement.

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BACKGROUND Juvenile Idiopathic Arthritis (JIA) is the most frequent chronic rheumatic disease in children. Some north american and canadian studies have shown that prevalence and incidence rates of JIA and other rheumatic diseases are higher in indigenous populations than in non-indigenous. In Brazil, there is a lack of knowledge about the epidemiology of JIA, especially in the Amazon region, where there are no previous studies about JIA. According to the Demographic Census of 2010, 817 thousand people declared themselves indigenous, and among these 37.4% are in the northern region of the country (25.4% in the states of Amazonas and Pará). The north region has 15,864,454 inhabitants, and among these 69.75% are in the states of Amazonas and Pará. Thus, we elected the State of Amazonas to carry out the epidemiological survey of JIA. MATERIALS AND METHODS This is a retrospective descriptive study carried out by consulting patients' charts from 2014 to 2017 in a tertiary pediatria rheumatology service in order to collect data regarding: gender, age of diagnosis, current age, ethnicity, naturalness, medication provided, subtype of the disease and the presence of complications, such as uveitis and macrophagic activation syndrome.

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