Oxaliplatin with 5-fluorouracil plus leucovorin (FOLFOX) has become the standard treatment in patients with colorectal cancer. Among known toxicities induced by oxaliplatin, hematological, gastrointestinal and neurological toxicities are common. However, acute pulmonary toxicity associated with oxaliplatin is unusual. One case of interstitial lung disease associated with the FOLFOX protocol is reported here.

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Many researchers have been focusing on the development of the new energy saving devices. The optoelectronic devices such as organic solar cells (OSCs) and organic light emitting diodes (OLEDs) have been regarded as the next generation energy saving devices. In addition, those devices can also be applied to the Internet of Things (IoT), which is the interconnection of identifiable objects through the wireless internet systems. In addition, IoT is expected to provide advanced connectivity of the devices, systems, and services.In this study, for future applications of smart farm and buildings, the flexible OLEDs were prepared by the spin coating and thermal evaporation methods. The stability of the devices by introducing of the hybrid encapsulation materials using organic and inorganic passivation materials were investigated. The lifetime of the devices are affected by the humidity and oxygen environment. Therefore, encapsulations using hybrid inorganic and organic materials of the devices would be important technologies in order to prevent the devices from the oxygen and moisture. As a result, the prepared OLED device with the hybrid encapsulation materials showed better stability and reliability compared with glass capped OLED devices.