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Conservation of olfaction is possible in selected cases of anterior skull base surgery when the lesion is unilaterally confined.

Funga l sinu sitis secondary to Pseudallescheria boydii is rare, as only 25 cases hav e been previously reported in the literature. Although Pboydii resembles Aspergillus on pathologic examination, it is typically resistant to amphotericin B. Therefore, culture is necessary to differentiate the two. Pati ents with P boydii sinusitis should generally be treat ed with a combination of surgery and antifungal therapy. Combination treatment is particularly important for immunocompromised pati ents with fungal invasion because morta lity among these patients is high. The prognosis is better for immunocompetent patients, even those with fungal invasion. We desc ribe a new case of invasive fungal sinusitis secondary to P boydii infection , and we review the literature on this emerging pathogen.

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