The present study aimed to review literature on studies of dengue cases conducted over 30 years in the state of Ceará. Between November 2015 and January 2016, articles published in Portuguese and English in 7 databases were searched using keywords and a Boolean operator. A total of 191 articles were identified in the databases; 133 were excluded according to the exclusion criteria, and 58 were included in the study. Of the 58 articles analyzed, 6 reported data from Brazil; including the Northeast region and the state of Ceará; 41 reported data for only the city of Fortaleza; 7 reported data for the state of Ceará; 4 reported data for cities in the interior of the state; and 3 included only children. The studies adopted different approaches and focused on different aspects of the disease. Study outcomes included the identification of serological, epidemiological, clinical, and laboratory characteristics; potential larvicides and biological predators of mosquitoes; potential antiviral agents; vector density characteristics; and educational dengue prevention and control strategies. Additionally, one vaccine trial was included. Although studies on dengue in the state of Ceará are scarce, they are encompassing, including several lines of research, and the number of studies and reports on dengue in the state of Ceará continues to increase.

Neurotuberculosis is a serious disease, occurring in about 5 to 10% of cases of extrapulmonary tuberculosis. The clinical spectrum varies according to the affected site (meningeal, cerebral parenchyma or spinal cord). Herein we present the case of a 32-year-old male patient with cough and weight loss who presented with hemiparesis and disorientation, receiving a diagnosis of neurotuberculosis using the Xpert MTB / RIF® test. The present case aims to report the clinical and neuroimaging data of an immunocompetent patient with neurotuberculosis.The definitive diagnosis is made by the detection of tuberculosis bacilli in cerebrospinal fluid. The RIF® Xpert MTB test has similar sensitivity and specificity to other diagnostic methods for tuberculosis and the advantage of providing information on resistance to rifampicin. The prognosis depends on the stage and onset of treatment.