Post-operative nausea and vomiting (PONV) is one of the most unpleasant complications following anaesthesia and surgery since long time. A non -randomized case control study of prevention of post operative nausea and vomiting with IV- Granisetron was done on 270 adult surgical patients who received general or spinal aneasthesia. All the patients were followed up to 48 hours after operation. A complete response was achieved in prophylaxis group as 92.6% and in control group as 90.4%(p-value=0.6637). In patient with PONV ,gender incidence is equal in prophylaxis group. Female incidence is higher in control group. Majority of patients (90 to 100 %) had PONV within 24 hours after operation. As there is insignificant difference in the achievement between prohylaxis group and control group, anti emetic prophylaxis is recommended only for patient with one or more risk factors for PONV. DOI:10.3329/jbcps.v27i3.4290 J Bangladesh Coll Phys Surg 2009; 27: 139-143
Granulosa cell tumour of ovary are rare hormonally active neoplasm characterized by indolent course, local spread with a preponderance for extremely late recurrence and high survival rate. We report a 60 year old lady presented in 2009 with aggressive looking growth in vulva 16 years after her total abdominal hysterectomy with Bilateral salphingo-ophorectomy with infracolic omentectomy for suspected stage granulosa cell tumour of ovary , confirmed by histopathology. She remained disease free for 13 years and in 2005 underwent resection of retroperitoneal mass with multiple peritoneal implant, confirmed to be a granulosa cell tumour after biopsy. Despite six course adjuvent combination therapy with complete response she presented after 4 years in 2009 with a second recurrence in vulva. She had tumour reductive surgery followed by chemotherapy and hormonal therapy but the disease was progressive. In conclusion late recurrence and repeat recurrence is a hallmark for granulosa cell tumour of ovary, so we emphasis the need for long term follow up and consider the possibility of recurrence when presented with acute abdomen after initial surgery for granulose cell tumour. But there is no standard management protocol and we review this patients treatment in the context of current literature.
JCMCTA 2012 ; 23 (2): 42-46
Recurrence of biliary symptoms following cholecystectomy either laparotomic or laparoscopic, is quite common. Causes are either biliary or extra-biliary. Symptoms of biliary origin chiefly depends on residual stones, biliary stricture, rarely depends on stones in cystic duct or gallbladder remnant. Diagnosis of stump-stones is difficult, mainly arising from USG, MRCP,CT-scan, ERCP. Completion cholecystectomy can be done by laparotomy or laparoscopically. We report two cases of stump-stones discovered after 10 years & 5 years following lap chole and minilap cholecystectomy respectively, who were diagnosed by USG, CT-scan and managed by open completion cholecystectomy. Stump-stones can be a possibility of post cholecystectomy syndrome even after 10 years and surgeons should be aware of it.
JCMCTA 2014 ; 25 (2) : 49-53
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