Objective: Glaucoma is a sight threatening disorder. Measuring the IOP with accuracy plays a pivotal role in diagnosing and monitoring glaucoma. The purpose of this study was to compare the values of non-contact tonometer; air-puff and GAT (Goldmann Applanation Tonometer) along with its correlation to central corneal thickness (CCT), in various IOP (intra-ocular pressure) groups. Methods: Cross-sectional, prospective study. 311 patients were enrolled in this study. IOP was taken in all patients with APT and GAT. CCT was also measured. Data was analyzed and correlated with the help of Bland-Altman, Pearson correlation and intraclass correlation analysis regarding APT, GAT and CCT, using SPSS 24.0 software. Results: The median IOP measured by APT and GAT was 14mmHg (range: 37) and 12mmHg (range: 16) where as the median CCT was 534µ (range: 44), respectively. At low (<10mm of Hg) and normal IOP (10-20mm of Hg) both instruments showed similar results but at higher IOP (21-30mm of Hg) GAT is concluded more accurate (P=<0.001). Conclusion: GAT showed a high agreement with APT over a wide range of IOP. However, at moderate and higher group of IOP, APT revealed overestimation of IOP compared to GAT. CCT also plays a significant role. Continuous...

Triple A Syndrome is an autosomal recessive entity involving multiple systems usually characterized by adrenal insufficiency, alacrimia and achalasia. The disease features include variable degrees of neurological and neuro-ophthalmic manifestations. Protein ALADIN encoded by the AAAS gene is found to be defective in Triple A Syndrome. Here we discuss a case series of five patients diagnosed as Triple A Syndrome. Clinically there was variable degree of optic atrophy in all the cases, which was further confirmed with spectral domain Optical Coherence Tomography The aim of this study was to publish the OCT based ONFL graphs of these unique cases, so that being an ophthalmologist we can take a multidisciplinary approach and decisions accordingly. doi: https://doi.org/10.12669/pjms.37.1.3310 How to cite this:Nasir J, Javed A, Arshad O, Chatni MH. Spectral Domain – Optical Coherence Tomography Findings in Triple-A Syndrome – A case series from Pakistan. Pak J Med Sci. 2021;37(1):267-271. doi: https://doi.org/10.12669/pjms.37.1.3310 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.