The adsorption equilibrium of carbon dioxide (CO 2 ), carbon monoxide (CO), nitrogen (N 2 ), methane (CH 4 ), and hydrogen (H 2 ), was studied at 303 K, 323 K, and 343 K, and pressures up to 7 bar, in titanium based MOF granulates, amino-functionalized titanium terephthalate MIL-125(Ti)_NH 2 . The affinity of the different adsorbates towards the adsorbent presented the following order: CO 2 > CH 4 > CO > N 2 > H 2 from the most adsorbed to the less adsorbed component. Subsequently, adsorption kinetics and multicomponent adsorption equilibrium were studied by means of single, binary and ternary breakthrough curves at 323 K and 4.5 bar with different feed mixtures. Both studies are complementary, and aim the syngas purification for two different applications, hydrogen production and H 2 /CO composition adjustment to be used as feed in the Fisher-Tropsch processes. The isosteric heats were calculated from the adsorption equilibrium isotherms and are 21.9 kJ mol -1 for CO 2 , 14.6 kJ mol -1 for CH 4 , 13.4 kJ mol -1 for CO, and 11.7 kJ mol -1 for N 2 . In the overall pressure and temperature range the adsorption equilibrium isotherms were well regressed against the Langmuir model. The multicomponent breakthrough experimental results allowed validation of the adsorption equilibrium predicted by the multicomponent extension of the Langmuir isotherm, and validation of the fixed-bed mathematical model. To conclude, two pressure swing adsorption cycles were designed and performed experimentally, one for hydrogen purification from a 30%/70% CO 2 /H 2 mixture (hydrogen purity was 100 % with recovery of 23.5 %), and a second PSA cycle to obtain a light product with a H 2 /CO ratio between 2.2 and 2.4 to feed to a Fischer-Tropsch processes. The experimental cycle produced a light stream with a H 2 /CO ratio of 2.3, and a CO 2 enriched stream with 86.6 % purity as heavy product. The CO 2 recovery was 93.5 %