Background/aims-The Y402H polymorphism in the complement factor H (CFH) gene is an important risk factor for age-related macular degeneration (AMD). Complement activation products and proinflammatory cytokines are associated with this polymorphism at the systemic level, but less is known of the associations in the outer retina of the genotyped eye. Here we investigate complement activation products and their role in nuclear factor (NF)-κB activation and gene expression of the NLRP3 inflammasome pathway.

This study identified risk factors associated with a higher prevalence of oGVHD DES in post-AHSCT patients with cGVHD.

Background-This study aimed to test the effects of a one-hour classroom-based workshop, led by medical students, on mental illness stigma amongst secondary school students.

Domestic swine, but not Yucatan, are a feasible model for future sinonasal research using standard FESS instruments.